Elucidating the Molecular Basis of pH Activation of an Engineered Mechanosensitive Channel
K. Immadisetty, A. Polasa, R. Shelton, M. Moradi
This paper uses molecular dynamics simulations to elucidate the atomic-level activation mechanism of an engineered MscL channel triggered by pH changes, identifying key structural changes and interactions involved.
bioRxiv · Mar 11, 2021 · PreprintBiophysics