The influence of the way of regression on the results obtained by the receptorial responsiveness method (RRM), a procedure to estimate a change in the concentration of a pharmacological agonist near the receptor
I. Ovary, G. Viczjan, T. Erdei, B. Takacs, R. Szekeres, N. Lampe, J. Zsuga, M. Szucs, Z. Szilvassy, B. Juhasz, R. Gesztelyi
This study evaluates different regression methods for the receptorial responsiveness method (RRM) and finds that two-model global fitting is most precise, while individual fitting is most accurate.
bioRxiv · Jun 23, 2023Pharmacology & Toxicology