Rajneesh Kumar

Estimating physical conditions supporting gradients of ATP concentration in the eukaryotic cell

The paper uses reaction-diffusion modeling to investigate conditions under which ATP concentration gradients can form in eukaryotic cells, finding that spatial clustering of sources and sinks enables large gradients.

Modelling benefits and costs of decision making and feedback control for organisms in changing environments

The paper models the tradeoffs of decision-making and feedback control in organisms under changing environments, showing when control mechanisms are most beneficial.

Fine-grained modelling of ATP dependence of decision-making capacity in genetic regulatory networks

This study uses fine-grained mathematical models to explore how ATP levels affect decision-making capacity in a two-gene regulatory network, showing higher energy supports more cell states.