Type I and III interferons differentially encode inflammatory gene activation through threshold control of ISGF3 dynamics
Henrry Dubon Martinez, Rajshree Chettiyar, Maya McAuley, Catera L. Wilder
This study shows type I and III interferons produce distinct inflammatory gene activation through different ISGF3 dynamics, with type III limiting high activity duration.
bioRxiv · Oct 2, 2026 · PreprintMolecular Biology