Beyond Viral Load: A Mechanistic Model of Virus-Immune Dynamics and Age-Dependent Influenza Severity
Reagan Johnson, Havilah Neujahr, Rodolfo Blanco, Esteban Abelardo Hernandez-Vargas
This paper develops a mechanistic model linking viral dynamics, immune responses, and symptom severity in influenza, showing that age-related immune changes drive disease severity beyond viral load.
bioRxiv · Aug 31, 2026 · PreprintSystems Biology