Gpr125 identifies myoepithelial progenitors at tips of lacrimal ducts and is essential for tear film.
Elena Spina, Rebecca Handlin, Julia Simundza, Angela Incassati, Muneeb A. Faiq, Anoop Sainulabdeen, Kevin C. Chan, Pamela Cowin
This study identifies Gpr125 as a marker for lacrimal duct progenitors and shows its essential role in tear film formation and its involvement in dry eye syndrome and blepharitis.
bioRxiv · Sep 15, 2020 · PreprintDevelopmental Biology