Estimating tumor mutational burden from RNA-sequencing without a matched-normal sample
Rotem Katzir, Noam Rudberg, Keren Yizhak
This paper develops a method to estimate tumor mutational burden from RNA-sequencing data without matched-normal samples, achieving high precision and recall in melanoma samples and showing association with patient survival.
Nature Communications · Jun 2, 2022Peer-reviewedGenomics