A subject-specific reversible folding model reveals geometry-driven white-matter organization
Besm Osman, Ruben Vink, Andrei C. Jalba, Kurt G. Schilling, Maxime Chamberland
The paper introduces a subject-specific cortical folding model that generates fiber orientations from cortical geometry, validated with fetal MRI and applied to adult data without diffusion inputs or machine learning.
bioRxiv · Dec 13, 2025 · PreprintBioengineering