Multiscale simulations reveal key features of the proton pumping mechanism in cytochrome c oxidase
Ruibin Liang, Jessica M J Swanson, Yuxing Peng, Marten Wikstrom, Gregory Voth
This paper uses multiscale simulations to analyze proton transport in cytochrome c oxidase, showing that proton pumping and chemical proton transfer are thermodynamically driven by electron transfer and kinetically distinct.
bioRxiv · Feb 24, 2016Biophysics