A mathematical model of ctDNA shedding predicts tumor detection size
S. Avanzini, D. M. Kurtz, J. J. Chabon, E. J. Moding, S. S. Hori, S. S. Gambhir, A. A. Alizadeh, M. Diehn, J. G. Reiter
This paper develops a mathematical model to predict tumor detection size based on ctDNA shedding, showing median detection sizes and lead times for early cancer detection.
bioRxiv · Feb 12, 2020Cancer Biology