Determination of the structure and dynamics of the fuzzy coat of an amyloid fibril of IAPP using cryo-electron microscopy
Z. F. Brotzakis, T. Löhr, S. Truong, S. E. Hoff, M. Bonomi, M. Vendruscolo
The paper develops MEMMI, a cryo-EM method that determines structure and dynamics of large systems, and applies it to study the fuzzy coat of an IAPP amyloid fibril.
bioRxiv · May 29, 2022Biophysics