A shift in aggregation avoidance strategy marks a long-term direction to protein evolution
S. G. Foy, B. A. Wilson, J. Bertram, M. H. J. Cordes, J. Masel
The paper shows that older genes have more interspersed hydrophobic residues compared to younger genes, indicating a long-term evolutionary trend toward reducing aggregation risk.
bioRxiv · Oct 23, 2018Evolutionary Biology