The inositol-requiring enzyme 1α/X-box protein 1 (IRE1α/XBP1) pathway of the unfolded protein response is impaired in pediatric cholestatic liver disease explants
A. Kriegermeier, A. Hyon, B. Lecuyer, S. Hubchak, X. Liu, R. Green
This study shows that the IRE1α/XBP1 pathway is underactive in pediatric cholestatic liver disease explants compared to normal and non-cholestatic controls.
bioRxiv · Mar 11, 2022 · PreprintCell Biology