Author

S. Subhadarshini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:diffusion model· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

H. Tandon· 1 shared J. Somarelli· 1 shared M. K. Jolly· 1 shared N. Srinivasan· 1 shared R. Sowdhamini· 1 shared S. Debnath· 1 shared S. Sahoo· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

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1 shared paperBiophysics

H. Tandon

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2 papers

Recent·Most cited

Single-Site Phosphorylation Elicits Structural, Dynamic, and Accessibility Changes in Proteins at both Proximal and Distal Regions to the Phosphosite.

S. Subhadarshini, H. Tandon, N. Srinivasan, R. Sowdhamini

This study investigates how phosphorylation affects protein structure, dynamics, and surface accessibility, revealing both local and distant changes in protein behavior.

bioRxiv · Nov 30, 2023 · PreprintBiophysics

Dynamical modelling of proliferative-invasive plasticity and IFN-gamma signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity

S. Subhadarshini, S. Sahoo, S. Debnath, J. Somarelli, M. K. Jolly

This study uses dynamical modeling to uncover how IFN-gamma signaling and proliferative-invasive transitions shape PD-L1 expression heterogeneity in melanoma, with experimental validation in cell lines and datasets.

bioRxiv · Jan 9, 2023 · PreprintCancer Biology