Leveraging Family History in Case-Control Analyses of Rare Variation
Claudia Solís‐Lemus, S. Taylor Fischer, Andrei Todor, Cuining Liu, Elizabeth J. Leslie, David J. Cutler, Debashis Ghosh, Michael P. Epstein
This paper introduces a new rare-variant association test that incorporates family history information, showing improved performance over standard methods in simulated data and a study of cleft lip and palate.
Genetics · Dec 16, 2019Peer-reviewedGenetics