Single-cell RNA sequencing and large-scale bulk combination with machine learning reveal gastric cancer-related macrophage heterogeneity
Saisai Gong, Yupeng Zhao, Sheng Yang, Tong Liu, Cheng yun Li, Yun Zhou, Geyu Liang
The paper uses scRNA-seq and bulk RNA-seq with machine learning to identify a C1QA-expressing TAM subset in gastric cancer linked to poor prognosis and tumorigenic functions.
bioRxiv · Oct 17, 2025 · PreprintCancer Biology