Author

Sam Paul Dhamodharan

University of Madras

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Assay:proteomics· 1 Approach:transformer / foundation model· 1 Research Focus:variant effect prediction· 1 Organism:virus· 1

Frequent Co-Authors

Abraham Rebairo J.iD· 1 shared Gugan KothandaniD· 1 shared Rashmi SiddalingappaiD· 1 shared Venkatachalam Rajakannan BiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiophysics

Abraham Rebairo J.ORCID

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1 paper

Recent·Most cited

A Fine-tuned ProtGPT2 (transformer model) for Predicting more Virulent SARS-CoV-2 variants and understanding its virulence by biophysical methods.

Sam Paul Dhamodharan, Abraham Rebairo J., Rashmi Siddalingappa, Venkatachalam Rajakannan B, Gugan Kothandan

This study predicts potential SARS-CoV-2 mutations using a ProtGPT2 model and evaluates their virulence through molecular dynamics simulations and binding free energy analysis.

bioRxiv · Jan 13, 2025 · PreprintBiophysics