RRM2B is frequently amplified across multiple tumor types: non-oncogenic addiction and therapeutic opportunities
Waleed Iqbal, Elena V. Demidova, Samantha Serrao, Taha ValizadehAslani, GAIL L. ROSEN, Sanjeevani Arora
The paper identifies frequent RRM2B amplification in multiple tumors, links it to DNA repair defects and poor outcomes, and suggests therapeutic opportunities.
bioRxiv · Sep 10, 2020 · PreprintGenomics