CD2AP's structure and oligomerization are compromised by the K301M mutation: implications for Nephrotic syndrome
Abrar H. Qadri, Raja Mani Trapathi, Iqball Faheem, Samiksha Meshram, Eswar R. Reddem, Ravishankar Ramachandran, Anil Kumar Pasupulati
This study investigates how the K301M mutation in CD2AP disrupts its oligomerization and interaction with Podocin, contributing to nephrotic syndrome and FSGS.
bioRxiv · Jan 9, 2026 · PreprintBiophysics