Expanding reproductive genetic screening through the inclusion of perinatal treatability
Tse Yen Tan, Sarah Haas, Xiaoke Gao, Judy Li, Sarah Araji, Alex Liu, Courtney E. Wimberly, Nina B. Gold, Stefan Rentas, Michael Duyzend, Kyle M. Walsh, Jennifer L. Cohen
The paper evaluates a reproductive genetic screening framework that includes genes with perinatal intervention potential, finding an individual-level number-needed-to-screen of 3.20 using gnomAD and 3.62 using All of Us.
medRxiv · Aug 27, 2026 · PreprintGenetic & Genomic Medicine