Small effect size leads to reproducibility failure in resting-state fMRI studies
Xize Jia, Na Zhao, Barek Barton, Roxana Gabriela Burciu, Nicolas Carrière, Antonio Cerasa, Boyu Chen, Jun Chen, Stephen A. Coombes, Luc Defebvre, Christine Delmaire, Kathy Dujardin, Fabrizio Esposito, Guoguang Fan, Federica Di Nardo, , Yu‐Feng Zang
This paper shows that small effect sizes in resting-state fMRI studies lead to reproducibility issues, even after multiple comparison corrections, and recommends meta-analysis of un-thresholded data for better results.
bioRxiv · Mar 20, 2018 · PreprintNeuroscience