Synthetic BiologybioRxivPreprint
Predictive profiling of SARS-CoV-2 variants by deep mutational learning
Joseph M. Taft, Cédric R. Weber, Beichen Gao…·Sai T. Reddy
This paper develops deep mutational learning to predict the impact of SARS-CoV-2 spike protein mutations on ACE2 binding and antibody escape, identifying potential variants and supporting vaccine and therapeutic development.