BioinformaticsBioinformaticsPeer-reviewed
Identifying differentially methylated sites in samples with varying tumor purity
Antti Häkkinen, Amjad Alkodsi, Chiara Facciotto…·Sampsa Hautaniemi
The paper presents a computational method to identify differentially methylated sites in heterogeneous tumor samples with varying cancer cell fractions, without needing normal controls or prior purity estimates.
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