An innate immune activation state prior to vaccination predicts responsiveness to multiple vaccines
Slim Fourati, Lewis E. Tomalin, MP. Mulè, Daniel G. Chawla, Bram Gerritsen, Dmitry Rychkov, Evan Henrich, HER. Miller, Thomas Hagan, Joann Diray‐Arce, Patrick J. Dunn, Ofer Levy, Raphaël Gottardo, Minnie Sarwal, JS. Tsang, , SH. Kleinstein
The paper identifies a pre-vaccination transcriptional state linked to pro-inflammatory genes that predicts higher antibody responses to multiple vaccines.
bioRxiv · Sep 26, 2021 · PreprintSystems Biology