Evolution of gene order in prokaryotes is driven primarily by gene gain and loss
Shelly Brezner, Sofya K. Garushyants, Yuri I. Wolf, Eugene V. Koonin, Sagi Snir
This study quantifies the contribution of gene gain and loss versus genome rearrangements to gene order evolution in bacteria and archaea, finding gene gain and loss dominate.
Proceedings of the National Academy of Sciences · Jun 11, 2025Peer-reviewedEvolutionary Biology