The Role of Ribose Modifications on the Structural Stability of Nucleotide Analogs with α-thiotriphosphate at the Active Site of SARS-CoV-2 RdRp
This study uses molecular dynamics simulations to investigate how ribose modifications interact with thio modifications in nucleotide analogs at the SARS-CoV-2 RdRp active site, revealing structural stability effects.
bioRxiv · Apr 11, 2025 · PreprintBioinformatics