Author

Shixiang Wu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Jianping CAI· 1 shared Wenjie GeiD· 1 shared Zhangquan Yang· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBioinformatics

Jianping CAI

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1 paper

Recent·Most cited

Method Choice, Not Biology, Determines In Silico Perturbation Results: A Systematic Evaluation of Eight Methods Across Four Datasets

Shixiang Wu, Shixiang Wu, Zhangquan Yang, Zhangquan Yang, Jianping CAI, Jianping CAI, Wenjie Ge

This paper evaluates eight in silico perturbation methods across four datasets, finding that only two consistently detect TF-to-pathway regulation, highlighting method choice's impact on results.

bioRxiv · Aug 19, 2026 · PreprintBioinformatics