Author

Shiyue Li

East China University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:multiome· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Qingchao JiangiD· 2 shared Ramon GrimaiD· 2 shared Zhixing CaoiD· 2 shared Y M WangiD· 1 shared Yiling WangiD· 1 shared Zhanpeng ShuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 13 mutual co-author links

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2 shared papersSystems Biology

Qingchao JiangORCID

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2 papers

Recent·Most cited

PRIME: scalable, robust inference of mechanistic cell states from multimodal single-cell counts via probability generating functions

Shiyue Li, Y M Wang, Qingchao Jiang, Ramon Grima, Zhixing Cao

PRIME infers mechanistic cell states from multimodal single-cell data by embedding counts in a probability generating function space, enabling robust kinetic analysis and clustering.

bioRxiv · Jun 9, 2026 · PreprintSystems Biology

Efficiency, accuracy and robustness of probability generating function based parameter inference method for stochastic biochemical reactions

Shiyue Li, Yiling Wang, Zhanpeng Shu, Ramon Grima, Qingchao Jiang, Zhixing Cao

This paper introduces a probability generating function-based method for parameter inference in stochastic biochemical reactions and shows it outperforms existing methods in efficiency, accuracy, and robustness.

PLoS Computational Biology · Apr 10, 2026Peer-reviewedSystems Biology