In silico discovery of pathogenic PD-L1 nsSNVs with altered glycosylation and immunotherapy binding
Kai Wei Tan, Shruti Vijay Khare, Joanne Ong, Carel Min Jie Tan, Sven Hans Petersen, Srinivasaraghavan Kannan, Chandrabhan Verma, Ann‐Marie Chacko
The paper identifies pathogenic PD-L1 nsSNVs that alter glycosylation and ICI binding through bioinformatics and experimental methods.
bioRxiv · Jun 17, 2025 · PreprintBioinformatics