CytoGem-XAI:A Hypergraph Neural Network Framework for Genome-Scale Metabolic Modeling and Interpretable Analysis
Shuaihua Chen, Teng Chen, Z. S. Xu, Lingling Zhang, Bei Gao, Jiali Mao
CytoGem-XAI combines hypergraph neural networks with interpretable analysis to improve metabolic modeling and prediction in E. coli, outperforming existing methods and revealing new essential nutrients.
bioRxiv · Jun 7, 2026 · PreprintBioinformatics