Molecular architecture of the tumor microenvironment caused by BRCA1 and BRCA2 somatic mutations in lung adenocarcinoma
Gaoming Liao, Xinbin Yang, Qi Liu, Shufeng Nan, Y. L. Liu, Jinwei Li, S. Joseph Huang, Ning Wang, Xionghai Qin, Gang Xu
This study examines BRCA1/2 mutations in lung adenocarcinoma, finding distinct immune and transcriptional patterns linked to different clinical outcomes and potential therapeutic targets.
bioRxiv · Apr 11, 2026 · PreprintCancer Biology