Author

Shuwen Shan

University of Göttingen

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Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:statistical model· 1

Frequent Co-Authors

Bertram BrenigiD· 1 shared Elisabeth DietschiiD· 1 shared Fangzheng XuiD· 1 shared Lilith SteingräberiD· 1 shared Marc HirschfeldiD· 1 shared Mirjam Spengeler· 1 shared Reiner AndagiD· 1 shared Reinhard H. Mischke· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperGenetics

Bertram BrenigORCID

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1 paper

Recent·Most cited

Christmas disease in a Hovawart family resembling human hemophilia B Leyden is caused by a single nucleotide deletion in a highly conserved transcription factor binding site of the F9 gene promoter

Bertram Brenig, Lilith Steingräber, Shuwen Shan, Fangzheng Xu, Marc Hirschfeld, Reiner Andag, Mirjam Spengeler, Elisabeth Dietschi, Reinhard H. Mischke, Tosso Leeb

The paper identifies a single nucleotide deletion in the F9 gene promoter of a Hovawart family causing hemophilia B resembling human hemophilia B Leyden, with reduced factor IX expression and altered transcription factor binding.

Haematologica · Mar 7, 2019Peer-reviewedGenetics