Identification of Cancer-associated Metabolic Vulnerabilities by Modeling Multi-objective Optimality in Metabolism
Ziwei Dai, Liyan Xu, Li‐Yan Xu, Kun Liao, Shuye Deng, Qiyi Chen, Qian Wang, Qian Wang, Shuaishi Gao, Bo Li, Luhua Lai
This study develops a multi-objective metabolic model to identify cancer-associated metabolic vulnerabilities by analyzing Pareto surfaces and validating predictions with experimental data.
Cell Communication and Signaling · Oct 10, 2019Peer-reviewedSystems Biology