Refractive index mapping below the diffraction limit via single molecule localization microscopy
Simon Jaritz, Lukáš Veľas, Anna Gaugutz, Manuel Rufin, Philipp J. Thurner, Orestis G. Andriotis, Julian G Maloberti, Simon Moser, Alexander Jesacher, Gerhard J. Schütz
This paper introduces a method combining SMLM and AFM to map refractive index at sub-diffraction resolution, revealing structural heterogeneity in collagen fibrils.
ACS Nano · Dec 26, 2025Peer-reviewedBiophysics