A Scalable Framework for Identifying Allelic Series from Summary Statistics
Zachary Ryan McCaw, Jianhui Gao, Rounak Dey, Simon Tucker, Yiyan Zhang, Jessica L. Gronsbell, Xihao Li, Emily B. Fox, Colm T. O’Dushlaine, Thomas W. Soare
The paper introduces COAST-SS, a method to identify allelic series using summary statistics, showing it is effective and robust to LD matrix misspecification.
The American Journal of Human Genetics · Oct 13, 2025Peer-reviewedGenetics