Controlled Noise: Evidence of Epigenetic Regulation of Single-Cell Expression Variability
Yan Zhong, Siwei Cui, Yongjian Yang, James J. Cai
This study investigates the link between chromatin accessibility and single-cell expression variability using scATAC-seq and scRNA-seq data from human hematopoietic cells, finding that chromatin accessibility explains much of the variability.
Bioinformatics · Jul 1, 2024Peer-reviewedBioinformatics