Author

Siyao Zhu

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Assay:metagenomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Ali R. ZomorrodiiD· 1 shared Hantao ZhangiD· 1 shared Nicholas A. Medearis· 1 shared Peng XuiD· 1 shared Yimeng KongiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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1 shared paperBioinformatics

Ali R. ZomorrodiORCID

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2 papers

Recent·Most cited

BiomeGPT: A foundation model for the human gut microbiome

Nicholas A. Medearis, Siyao Zhu, Ali R. Zomorrodi

BiomeGPT is a transformer-based foundation model pretrained on human gut metagenomes to predict host health status and reveal microbial signatures linked to diseases.

bioRxiv · Jan 5, 2026 · PreprintBioinformatics

ICE: An imputation framework for detecting cellular senescence using weak single-cell signatures

Peng Xu, Hantao Zhang, Siyao Zhu, Yimeng Kong

The paper introduces ICE, a framework for detecting senescent cells using weak single-cell markers, improving detection accuracy from 56% to 98% in pancreatic cells.

bioRxiv · May 25, 2025 · PreprintGenomics