Albumin inhibits the activation of hepatic stellate cells by suppressing TGF-β/Smad3 signaling via IL-1β
Ji Hoon Park, Jang‐Hyun Kim, So-Young Choi, Kiweon Cha, Heekyung Park, Jung Eun Lee, Boram Lee, Ji Wook Moon, Sun-Hwa Park, Jae Min Lee, Hong Sik Lee, Junseo Oh
This study investigates how albumin and its derivative R-III inhibit hepatic stellate cell activation by suppressing TGF-β/Smad3 signaling through IL-1β and RA sequestration.
bioRxiv · Aug 31, 2019 · PreprintMolecular Biology