Flexibility and Hydration of the Qo Site Determine Multiple Pathways for Proton Transfer in Cytochrome bc1
Sofia R. G. Camilo, Guilherme M. Arantes
This study uses molecular dynamics simulations to investigate proton transfer pathways in the Qo site of cytochrome bc1, revealing flexible side chains, multiple quinol binding modes, and a hydrogen bond network facilitating proton transport.
Journal of Chemical Information and Modeling · Jun 10, 2025Peer-reviewedBiophysics