Pitx2-associated early-onset glaucoma alters corneal innervation and sensory function in a sex-specific manner
Solange Sarkis, Luna Dumon, Mélissa Girard, Chantal Cazvieille, Marina Schverer, Vincent Daïen, Bianca Johansen, Cécile Delettre, Chloé Chamard, Frédéric Michon
This study shows that Pitx2-associated glaucoma causes sex-specific changes in corneal nerve structure and sensory function, with females showing more inflammatory and stress-related changes than males.
bioRxiv · May 1, 2026 · PreprintNeuroscience