To pack or not to pack: revisiting protein side-chain packing in the post-AlphaFold era
Sriniketh Vangaru, Debswapna Bhattacharya
The paper benchmarks PSCP methods on CASP datasets, showing they work well with experimental data but struggle with AlphaFold-generated structures, and explores confidence-aware integration with limited success.
Briefings in Bioinformatics · May 1, 2025Peer-reviewedBioinformatics