Revealing cancer driver genes through integrative transcriptomic and epigenomic analyses with Moonlight
Mona Nourbakhsh, Yuanning Zheng, Humaira Noor, Hongjin Chen, Subhayan Akhuli, Matteo Tiberti, Olivier Gevaert, Elena Papaleo
The paper introduces Moonlight2, an updated framework that integrates transcriptomic and epigenomic data to identify cancer driver genes, finding 33, 190, and 263 epigenetically driven genes in three cancer subtypes.
PLoS Computational Biology · Apr 21, 2025Peer-reviewedBioinformatics