Genetic regulatory mechanisms of smooth muscle cells map to coronary artery disease risk loci
Boxiang Liu, Milos Pjanic, Ting Wang, Trieu Nguyen, Michael J. Gloudemans, Abhiram S. Rao, Victor G. Castano, Sylvia Nürnberg, Daniel James Rader, Susannah Elwyn, Erik Ingelsson, Stephen B. Montgomery, Clint L. Miller, Thomas Quertermous
The paper identifies five genes modulating coronary artery disease risk through smooth muscle cells by integrating eQTL and GWAS data with transcriptomic and epigenomic analyses.
The American Journal of Human Genetics · Aug 23, 2018Peer-reviewedGenomics