EVOLUTIONARY CO-OPTION OF AN ANCESTRAL CLOACAL REGULATORY LANDSCAPE DURING THE EMERGENCE OF DIGITS AND GENITALS
A. Hintermann, C. C. Bolt, M. B. Hawkins, G. Valentin, L. Lopez-Delisle, S. Gitto, P. B. Gomez, B. Mascrez, T. A. Mansour, T. Nakamura, M. P. Harris, N. H. Shubin, D. Duboule
The paper shows that the regulatory landscape controlling Hoxd gene expression in limbs was co-opted from an ancestral cloacal program in tetrapods.
bioRxiv · Mar 24, 2024Evolutionary Biology