Dynamics of p53 DNA binding sites contributes to functional selectivity of p53-driven gene expression
J. Safieh, A. Chazan, P. Vyas, H. Saleem, Y. Danin-Poleg, D. Ron, T. E. Haran
This study shows that DNA flexibility of p53 response elements influences the timing and efficiency of p53-driven gene expression, affecting cellular responses to stress.
bioRxiv · Sep 18, 2021 · PreprintBiochemistry