Sleep deprivation constrains dynamic configurations of integrated and segregated brain states impacting cognitive performance
Nathan E. Cross, Florence B. Pomares, Makoto Uji, Aude Jegou, Alex Nguyen, Kangjoo Lee, Ümit Aydın, Aurore A. Perrault, Christophe Grova, T.T. Dang-Vu
This study shows sleep deprivation reduces brain network flexibility by altering thalamic regulation and coupling with cortical networks, leading to cognitive impairments.
bioRxiv · Oct 21, 2025 · PreprintNeuroscience