Using Biological Constraints to Improve Prediction in Precision Oncology
Mohamed Omar, Wikum Dinalankara, Lotte Mulder, Tendai Coady, Claudio Zanettini, Eddie L. Imada, Laurent Younes B, Donald Geman, Luigi Marchionni
The paper develops mechanistic classifiers using biological constraints to improve the robustness and interpretability of gene signatures in cancer prediction.
iScience · Feb 2, 2023Peer-reviewedBioinformatics