Hippo signaling differentially regulates distal progenitor subpopulations and their transitional states to construct the mammalian lungs
Kuan Zhang, Madhuri Basak, Youssef Zaher, Erica Yao, Shao‐An Wang, Thin Aung, Pao‐Tien Chuang
This study uses single-cell analyses to show Hippo signaling regulates SOX9+ progenitor subpopulations and their transitions to generate lung structures in mice, with some parallels in human lungs.
Nature Communications · Apr 3, 2026Peer-reviewedDevelopmental Biology