Mechanistic Modeling Quantifies The Influence Of Tumor Growth Kinetics On The Response To Anti-Angiogenic Treatment
Thomas D. Gaddy, Qianhui Wu, Alyssa D. Arnheim, Stacey D. Finley
This study uses computational modeling to show that tumor growth kinetics influence the response to anti-VEGF treatment, with nonlinear dependence on VEGF receptor expression.
PLoS Computational Biology · Dec 21, 2017Peer-reviewedSystems Biology