Cardiometabolic stress induces atrial myopathy in mice, characterized by structural remodelling, metabolic dysfunction, and incomplete transcriptional recovery.
Jacques Couët, Diwaba Carmel Teou, Audrey Morin-Grandmont, Nicolas Le Bos, Thomas Le Bos, Emylie-Ann Labbé, Sara-Ève Thibodeau, Vincent Joseph, Marie Arsenault
This study shows that cardiometabolic stress causes atrial myopathy in mice, with partial recovery of metabolic and transcriptional changes after stress removal.
bioRxiv · Oct 13, 2026 · PreprintPhysiology